Oxycodone is an opioid agonist and therefore has abuse potential and risk of fatal overdose from respiratory failure. Addiction may occur in patients who obtain oxycodone illicitly or in those appropriately prescribed the drug. I have been on a high dose of oxycodone for Lupus for the past 8 months. I take up to 150 MG a day of oxycodone, I am trying to get off because I feel as if I don't need the meds anymore, I have found a different non-narcotic to help ease the pain. Medical uses. Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient. It may improve quality of life in certain types of pain. It is unclear if use in chronic pain results in improved quality of life or ongoing pain relief. Actavis, Oxycontin, Xanax, Oxycodone, Adderall, Hydrocodone, Percocets, Roxicodone and many more pain pills available The 10 refers to the amount of Oxycodone or Hydrocodone in there. The 325 is the mg of the Tylenol or Acetaminophen in it. Oxycontin vs Oxycodone. A number of people wonder if there is a difference between oxycontin and oxycodone. Are they the same medicines? Is oxycodone just a generic name for oxycontin? Oxycodone is Percocet. Generally a 5mg Percocet sells for between $4 and $5 depending on your area. If you are referring to OxyCONTIN then that generally sells for $1 per milligram. MedsChat is a popular drug forum. Featuring frequently updated message boards and an extensive index for medicine, health conditions, and drug information. Detailed Oxycodone dosage information for adults and children. Includes dosages for Pain and Chronic Pain; plus renal, liver and dialysis adjustments. I got down to about 30mg/day (the OxyContin 2x/day and 10mg oxycodone - 5mg at bedtime and another 5mg in the middle of the night when I would wake up).